New
Paradigms
These new paradigms
are conclusions derived from the physico-mathematical analysis and
interpretation of the Respiratory Pulse and other simultaneous
parameters, converging to organic dynamics for Life in the Atmosphere of the Earth.
The Respiratory Pulse
The Respiratory Pulse is the Resultant,
at the pleural level, of the autonomic cyclic dynamics of the Lung in its
thoracic ensemble, to which it integrates from the very moment of birth. These
dynamics achieve circulation of the atmospheric air up to the alveolar units,
in balance of time and force with the circulating arterial and capillary blood,
leading to gas exchange.
The pulmonary dynamics are
also natural processes for adaptation of the Living Beings and their balanced
integration with the Atmosphere, within the geographical limits of the species,
relative to the mass of air per volume unit.
One of these kinds of cycles,
is carried out by the lobar bronchi under command of the Vagus nerve,
for renovation of volume masses of air,
simultaneously achieving integration of the individuals with the Atmosphere, at
the geographical level of the species genetically programmed adaptation, while
also performing pulmo-cardio-circulatory integration and balance, for gas
exchange at the alveolar-capillary units, this latter by means of the other
kind of dynamic cycles, realised by the lobular bronchioles under
Sympathetic command
The Primary role of the Lung
is integration and balance of Organic Dynamics and Universal Dynamics, by means
of the Atmosphere, at the very moment of birth and its cyclic reaffirmation
throughout Life.
Therefore, being born means
the self balanced dynamic integration of the Foetus with the Atmosphere.
The mass per volume unit of
the air is the physic-mathematical natural factor enabling that integration.
The Living Being in the Atmosphere of
the Earth
This integrated dynamic
balance of the whole Organic System of Fluids is the role of the Respiratory
Apparatus, accomplished under active command of the Lung and the Central
Nervous System’s rhythm and force control.
Air mass per volume
unit is the physic mathematical factor determining the distribution of species
and individuals at different levels of the Atmosphere, regulated by the Lung,
in accordance with the equation F = m . a,
and the balance programmed in their genes.
Pulmonary
lobar kinetic and kinematics
Pulmonary lobar kinetics and
kinematics, under Vagus command, accomplish integration and cyclic adaptation
of each individual with the Atmosphere in their Environment, by means of the inspired
volume-mass of air
Insufficient pulmonary
expansion, due to low volume-mass of inspired air causes imbalance in organic
fluid circulation, as a factor leading to visceral oedema, as happens in the
evolution of Acute High Altitude Sickness
Pulmonary
lobular kinetic and kinematics
Alveolar-capillary rhythm and
pressure balance to enable air distribution among the alveoli, for gas exchange
with the blood.
Capillary blood hypertension
is a cause of pulmonary oedema.
Alveolar air hypertension is
a cause of gaseous emboli
Chronic, long lasting over
many years, increased alveolar kinetics and kinematics is a cause of the
mechanical destruction of their thinnest structures characterising Pure
Pulmonary Emphysema
Respiratory
Functional Pathologies
Respiratory functional
pathologies must be re-interpreted from the perspective of the Respiratory
Pulse and derived new paradigms
Pure Pulmonary Emphysema
Pure pulmonary
emphysema is caused by hyper-kinetics of
the pulmonary lobular structure due to Sympathetic-Adrenergic
hyperactivity. Nicotine is a potent Adrenergic drug, therefore, the smoking
habit and Nicotine contaminated environment is the cause of the widespread
prevalence of Emphysema.
Acute High Altitude Sickness
Each living species is
genetically designed for integration with the Atmosphere, from the very moment
of birth, followed by cyclic adaptation to different levels of altitude, within
the limits of each specie, relative to the mass of air per volume unit.
The Respiratory Pulse is the
Resultant, on the pulmonary surface, in the pleural space, of the cyclic
autonomic dynamics of the Lung in its thoracic ensemble, to which it
automatically integrates, via reflex, from the very moment of birth, by means
of the viscero-somatic Pulmo-Diaphragmatic or Vago-Phrenic reflex. This
autonomic dynamics is the process for the newborn integration and adaptation
with the Atmosphere of its environment.
Human specie’s adaptation
level is comprised between sea level and about 3000 and 3500 meters
approximately; farther on, pulmonary functional insufficiency shall manifest as
the known Acute High Altitude Sickness, for which I propose the name “Syndrome
of Acute Pulmonary Insufficiency at High Altitude”.
Curare and derived products,
among others, once very much used in anaesthesia has been cause of
post-operatory complications, decerebration and death
Sudden death following Adrenaline injection